Training

Tailored Training Ideas

E-phys Solutions aims to provide a complete training package entirely tailored to your specific needs. Every research group has its own strengths and weaknesses, dependent on staff experience, research focus and available equipment. Every group has its own recording requirements, dependent on brain areas and activity in question.

Often the theoretical background is insufficient to make proper decisions about e-phys approaches, but advice on equipment and consumable can be invaluable as well.

 

 

 

 

 

 

 

 

 

 

 

 

 

If interested, E-phys Solutions first conducts a form-based training-needs analysis and then we communicate directly with you to identify the type of training that would benefit most, based on the desired applications.

 

  • Any necessary theoretical background is provided through interactive seminars and relevant references.

 

  • Hands on training in preparation of electrodes (e.g. ECoG screw, wire electrodes and tetrodes) and electrode-interface boards.

 

  • Training in placing and fixing of electrodes, electrode-interface boards and/or cannulae in rat/mouse cadavers.

 

  • Hands on training in placement and fixing using aseptic surgical techniques in live animals, as allowed by the local animal experiment laws and regulations.

 

  • Training in animal aftercare and actual recording from the implanted devices and administering stimulations and drugs.

 

  • Advice on signal analysis, dependent on the acquisition/analysis software used.

 

 

 

 

Areas E-phys Solutions Can Provide Training

Neurophysiological processes underlying brain activity

  • Single neuron phsyiology
  • Neuronal synchronisation
  • Brain activity modulation

Biophysics underlying electrophysiological recordings

  • Single unit recording with tetrodes
  • Multichannel probe recordings
  • Bipolar/unipolar wire electrode recordings
  • Skull screw ECoG
  • Skalp EEG recordings

Recording techniques

  • Electrode preparation
  • Electrode placement approaches
  • Electrode-interface board selection
  • Tethered recording solutions
  • Wireless recording solutions
  • Safe (dis)connection techniques
  • Conditioning chamber recording
  • Video recording synchronisation

Signal analysis principles

  • Signal cleaing and filtering
  • Spectral analysis
  • Coherence analysis
  • Current-source density analysis
  • Behaviour-specific epoch selection

Drug/stimulus adminstration

  • Electrical stimulation electrodes
  • Light guides for optogenetic stimulation
  • Guide cannula for acute administration
  • Pump-operated chronic administration

Surgery techniques

  • Equipment selection
  • Anaesthesia
  • Brain access
  • Electrode placement and fixing technioques
  • Electrode-interface board fixing
  • Wound closure

Animal wellbeing

  • Aseptic techniques
  • Post-surgery analgesia
  • Housing conditions
  • Treating Infections
  • Food restriction regimes

 

 

 

 

The only good thing to do with good advice is pass it on; it is never of any use to oneself.” Oscar Wilde

 

Bespoke training for in vivo electrophysiology